Use of amantadine in Parkinson's disease. Results of a double-blind trial.

نویسندگان

  • V Dallos
  • K Heathfield
  • P Stone
  • F A Allen
چکیده

In a four-week double-blind trial of 62 patients with Parkinsonism 29 were treated withamantadine and 33 with a placebo. Modest but statistically significant improvement was observed in the first group, optimum benefit occurring after the first two weeks. Patients' reactions to the drug were favourable in 79%, and side effects were insignificant. Though amantadine appears to be a useful additive drug in the treatment of Parkinsonism, its value as a single treatment is as yet undetermined.

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عنوان ژورنال:
  • British medical journal

دوره 4 5726  شماره 

صفحات  -

تاریخ انتشار 1970